Guidelines
Acute Renal Failure
- Pre-renal
- hypovolaemia
- hepatorenal syndrome
- atheroembolic disease/ renal vein thrombosis
- infection / sepsis
- Renal
- Toxins / medication (NSAIDs, aminoglycosides, iodinated contrast, Li, phosphate)
- Rhabdomyolysis
- Haemolysis
- Multiple myeloma (: hypercalcaemia / cast nephropathy) Goldschmidt'00
- Acute Glomerulonephritis:
- Thin Basement Membrane Disease (AD)
- Non-proliferative
- Minimal change GN: 80% of NS in children: 90% cured after 3/12
- Focal Segmental Glomerulosclerosis (FSGS): due to reflux nephropathy, Alport syndr, heroin, HIV; presents as NS
- Membranous GN (MPGN): mixed nephrotic/nephritic picture, usu idiop, sometimes Ca, hepatitis, malaria, Penicillamine, SLE, shunt nephritis; 1/3 static, 1/3 remission, 1/3 ESRF
- Proliferative
- IgA nephropathy (Berger's disease): most common worldwide: macroscopic haematuria, occas NS; often young m 1-2d post URTI/GI infection; Tx: ACE-I (not steroids); variable prognosis, 20% ESRF;
- Henoch-Schonlein purpura (HSP): systemic variant of IgA nephropathy: small vessel vasculitis
- Post-infectious: classically post Strep pyogenes (10-14d post skin/pharyngeal infection)
- Mesangiocapillary ?GN
- Rapidly progressive GN (Crescentic GN)
- AntiGBM (Goodpasture's)
- vasculitic disorders
- Wegener's granulomatosis
- acute lupus nephritis
- Post-renal
- Medication interfering with bladder emptying
- BPH / Prostate Cancer
- kidney stones
- abdominal malignancy
- obstructed urinary catheter
Renal Registry - Standards
for patients on haemodialysis [Audit Dr Smithard, 10-Nov-08]
- Epo prescription !00%
- Hb>10g/dL
- Ca:2.2-2.6mM/L
- K:3.5-6.4mM/L
- Chol:<5mM/L
- Phosphate:<1.8mM/L
- PTH:<4xULN=4x56=224
- native fistula/graft:>80%
- BC:20-26mM/L
- pre-dialysis BP:<140/90
- post-dialysis BP:<130/80
- HbA1c:<7%
- Ferritin>100
- Ca-PO4-product:<4.8
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