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Src: ppt

Anaemia of Acute Illness

  • 95% of ICU patients anaemia by day 3
  • 50 [85]% of patients [>1wk on ICU] receive transfusions on ICU in US, avg 9.5 units, 40% during 1st week
  • acute blood loss accounts only for 35% of transfusions


  • diagnostic phlebotomy (accounts for 20% of total blood loss, ~60-80mL/day)
  • occult/overt bleeding (wounds, drains, GIT)
  • underproduction (blunted epo response, epo gene inhibition by cytokines, inflammation, altered iron metabolism & eryhtropoiesis)
  • haematologically similar to anaemia of chronic disease (low iron, low TIBC, nml/hi Ferritin)