Lipid modification
Diagnostic criteria for FH using Simon Broome register
- (1) TC>{7.5|6.7} or LDL-C>{4.9|4} in {adult|child} pre-Tx or highest on Tx
- (2) definite FH= (1) PLUS: {tendon xanthomata in pt or 1st/2nd degree relative|DNA-based evid of LDL-R mutation or defective apo B-100}
- (3) possible FH= (1) PLUS: FHx of MI <{60|50}y in {1st|2nd} degree relative OR: TC>{7.5|6.7} in {adult|<16y} 1st|2nd degree relative
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